Thursday, December 2, 2010

Couch Potato Effect: Missing Protein Leaves Mice Unable to Exercise

A group of researchers have come up with a new model displaying muscle functions. The mice keep a steady body weight but do not have the energy to exercise. They found that aging, diabetes, obesity, and other chronic illnesses can lead to this "couch potato" effect. In humans, the PGC-1 allows us to exercise unless we are obese and these levels are low. In the mice without PGC-1 acted normal but were unable to walk on a treadmill. This study led to the conclusion that if you are deficient of PGC-1 you have dysfunctional mitochondria resulting in diabetes.

I think that this was a good study because they need to figure more out about diabetes. They have found just another source but I think they need to keep researching. I know lots of people who have diabetes and they wished they new more. I am glad I don't have diabetes because I love to exercise. I would hate to sit on the couch all day but if that was all I knew I guess it wouldn't make a difference.

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